Concept of Complementation Using Human Genetics

 

Concept of Complementation Using Human Genetics

Since the mutations are recessive, the offspring will display the wild-type phenotype. A complementation test (sometimes called a cis-trans test) can be used to test whether the mutations in two strains are in different genes. Complementation will not occur if the mutations are in the same genes.

            Complementation test, is also called cis-trans test, in genetics, test for determining whether two mutations associated with a specific phenotype represent two different forms of the same gene (alleles) or are variations of two different genes.

Complementation test